Jack: I wish I could be a good father (so I could be with Kate).
Desmond: I wish I could have Widmore's approval (so I could be with Penny).
Charlie: I wish Drive Shaft never broke up.
Hurley: I wish I was the luckiest man alive.
Sawyer: I wish I never wrote that letter.
Kate: I wish I hadn't killed my stepfather.
Sayid: I wish Nadia was safe.
Daniel: I wish I never became a physicist.
Locke: I wish my father loved me.
Jin & Sun: I wish I hadn't ruined my marriage.
Claire: I wish 815 never crashed.