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This is just a random thought but after Desmond hit locke with the car and he is laying on the ground twitching his whole body was twitching, including his legs. If he has no control over his legs would they twitch as well? Since Locke is already with his "True Love" perhaps through Desmond hitting him with the car (or something Jack will do once Locke reaches the hospital) which will give Locke use of his legs again, which will trigger his memories of the Island... Just a thought