Carbonell has won awards such as The ALMA Awards 1999 ALMA Award Outstanding Actor in a Comedy Series for Suddenly Susan and The Star on the Horizon Award (President Award) at the Ft. Lauderdale International Film Festival in 2003. He has been nominated for numerous other awards at the ALMA Awards and NCLR Awards.
He has appeared in House, Monk, Daybreak (created by Paul Zbyszewski), Law and Order, Scrubs, and most recently Smokin' Aces, among many more. During the time the Lost episode "Not in Portland" was exhibited, Carbonell was also playing a recurring role in Cold Case.
One of his prominent and most remembered TV roles was in the superhero sitcom The Tick, playing the character Batmanuel.
Carbonell played a Cuban man who fails in a mission to assassinate President Batista in the Andy Garcia-directed feature film The Lost City.
He met his wife, Shannon Kenny while they were both working in the movie Attention Shoppers.
His character in the film Smokin' Aces, (Pasquale Acosta S.A. Gerald Diego), is the only one who shares screen time with Matthew Fox's character (Bill, Security Super). In that scene, Carbonell's character kills Fox's character. Also starring in the movie is Lost actor Kevin Durand.
Carbonell was 42 during the final season of Lost. (source 2)
He appeared as a guest star in the TV series Person of Interest (which stars Michael Emerson as a main character) in the episode Most Likely to.... Nestor's character never met with Michael Emerson's character, though Michael's character saw his pictures and had information on him.