In a flashback, Locke awakens in pain after his operation. His mother enters and explains that she approached him at his father's instructions to con him out of his kidney. Locke tears out his IV tube and starts crying. In the next scene, he drives up to his father's house and tries to enter, but Eddie doesn't let him. Locke goes up to the gate nonetheless, then drives off, beating his car's steering wheel and roof in despair.
In the present day, Locke beats the hatch and yells at the Island in anger and desperation. From within the hatch, a light comes on.
Full list of appearances
"Locke'd Out Again" and its variations play during the following scenes:
- Locke realizes that he has regained the power to walk. ("Walkabout")
- Jack resuscitates Charlie (alternate cut). ("All the Best Cowboys Have Daddy Issues")
- In a flashback, Locke learns of his father's con. In the present day, Locke bangs at the hatch door. ("Deus Ex Machina")
- Locke apologizes to Shannon for Boone's death. ("The Greater Good")
- Locke's father tells him to stop seeing him. ("Orientation")
- Locke promises Helen he'll stop going to his father's house. ("Orientation")
- Helen convinces Locke to take a "leap of faith" and choose her over his father. ("Orientation")
- Locke forgives his father at the funeral. ("Lockdown")
- Kate and Hurley dig Ana-Lucia and Libby's graves. ("Three Minutes")
- Locke recalls with Desmond banging at the hatch. ("Live Together, Die Alone, Part 2")
- Locke and Eddie Colburn arrive at the commune. ("Further Instructions")
- Locke learns he is paralyzed. ("The Man from Tallahassee")
- Having failed to kill his father, Locke walks through the Others in disgrace. ("The Brig")
- Nurses place John, newly born, in an incubator. ("Cabin Fever")
- Jack recalls his and Locke's last meeting. ("Because You Left")
- Locke recounts to Sawyer his time banging on the Hatch. ("The Little Prince")
- In the chamber below the Orchid, Locke learns he has to die. ("This Place Is Death")
- Eloise gives Jack Locke's suicide note. ("316")
Immediately after recovering from the crash, Locke found his paralysis was miraculously cured. ("Walkabout")
- Locke meets Walt. ("The Life and Death of Jeremy Bentham")
- Jacob revives Locke after his fall. ("The Incident, Part 1")
- The survivors bury Locke. ("The Substitute")
- The Man in Black insults Locke's faith while talking to Jack. ("The Last Recruit")
- After death, Locke remembers his time on the Island. ("The End")
"Can't Keep Locke Down", "Closure", "Locke-about", "Making Up for Lost Time", "The Science of Faith", "The Final Countdown" and "Shannonigans" use the theme from "Locke'd Out Again". The theme also influences Locke's third and fourth themes, his flash sideways theme and FLocke's theme.
The title places Locke's name into the phrase "locked out again." The piece's main scene shows Locke locked out in two situations: he bangs against his father's locked gates and the locked hatch. He's also metaphorically locked out in both cases—emotionally and spiritually, respectively.